H-Inv ID |
HIT000053868 |
H-Inv cluster ID |
HIX0001265
|
H-Inv protein ID |
HIP000064675
|
Accession number |
BC052998.2
|
CAGE tag ID |
NA
|
EST ID |
NA
|
Genomic location
|
Chromosome |
1 |
Location |
1q23.3
|
Position |
162602272-
162750246
|
Strand |
+
|
Transcript feature
|
NO;
|
Coding potential
|
Protein coding;
|
Definition |
Discoidin domain-containing receptor 2; Discoidin domain receptor 2; EC=2.7.10.1; CD167 antigen-like family member B; Discoidin domain-containing receptor tyrosine kinase 2; Neurotrophic tyrosine kinase, receptor-related 3; Receptor protein-tyrosine kinase TKT; Tyrosine-protein kinase TYRO10; AltName: CD_antigen=CD167b; Precursor; |
Similarity category
|
Category: Identical to known human protein(Category I).
|
Identical to known human protein (Q16832)
[Identity/coverage = 100.0%/100.0%] to
Homo sapiens (Human). protein.
|
Gene family / group |
NA
|
Gene symbol/name |
HGNC symbol |
DDR2
|
HGNC aliases |
"discoidin domain receptor family, member 2"
|
HGNC name |
discoidin domain receptor tyrosine kinase 2
|
DDBJ |
DDR2
|
UniProt |
DDR2
|
EC number |
EC 2.7.10.1receptor protein-tyrosine kinase;
|
KEGG metabolic pathway |
04020
:Calcium signaling pathway;
04060
:Cytokine-cytokine receptor interaction;
04210
:Apoptosis;
04320
:Dorso-ventral axis formation;
04360
:Axon guidance;
04370
:VEGF signaling pathway;
04510
:Focal adhesion;
04520
:Adherens junction;
04540
:Gap junction;
04640
:Hematopoietic cell lineage;
04730
:Long-term depression;
04810
:Regulation of actin cytoskeleton;
04910
:Insulin signaling pathway;
04912
:GnRH signaling pathway;
04930
:Type II diabetes mellitus;
05050
:Dentatorubropallidoluysian atrophy (DRPLA);
05120
:Epithelial cell signaling in Helicobacter pylori infection;
05210
:Colorectal cancer;
|
PubMed ID |
8247548;
9659899;
14702039;
15489334;
16140923;
16186104;
16186108;
16626936;
16710414;
17344846;
17665456;
17703188;
18201965;
18669648;
19110212;
19369195;
20004161;
20223752;
20564243;
20734453;
21568710;
ALL;
|
Related H-InvDB links |
Similarity Search Tool
|
Database links |
RefSeq |
NA
|
Ensembl |
NA
|
Entrez Gene |
Entrez Gene ID:4921;
|
KEGG GENES |
KEGG GENES(4921);
|
GeneCard |
DDR2;
*GeneCards is provided free to academic non-profit institutions.
|
etc |
Human-Gene diversity Of Life-style related Diseases;
|
Curation status |
Auto-annotated
|
Notes |
NA
|