H-Inv ID |
HIT000266029 |
H-Inv cluster ID |
HIX0010715
|
H-Inv protein ID |
HIP000090861
|
Accession number |
BC082992.1
|
CAGE tag ID |
NA
|
EST ID |
NA
|
Genomic location
|
Chromosome |
12 |
Location |
12q13.2
|
Position |
56473970-
56496591
|
Strand |
+
|
Transcript feature
|
Representative transcript;
Splicing isoform
|
Coding potential
|
Protein coding;
|
Definition |
Receptor tyrosine-protein kinase erbB-3; EC=2.7.10.1; Proto-oncogene-like protein c-ErbB-3; Tyrosine kinase-type cell surface receptor HER3; Precursor; |
Similarity category
|
Category: Identical to known human protein(Category I).
|
Identical to known human protein (P21860)
[Identity/coverage = 100.0%/100.0%] to
Homo sapiens (Human). protein.
|
Gene family / group |
NA
|
Gene symbol/name |
HGNC symbol |
ERBB3
|
HGNC aliases |
"lethal congenital contracture syndrome 2", "v-erb-b2 avian erythroblastic leukemia viral oncogene homolog 3"
|
HGNC name |
erb-b2 receptor tyrosine kinase 3
|
DDBJ |
ERBB3
|
UniProt |
ERBB3
|
EC number |
EC 2.7.10.1receptor protein-tyrosine kinase;
|
KEGG metabolic pathway |
04020
:Calcium signaling pathway;
04060
:Cytokine-cytokine receptor interaction;
04210
:Apoptosis;
04320
:Dorso-ventral axis formation;
04360
:Axon guidance;
04370
:VEGF signaling pathway;
04510
:Focal adhesion;
04520
:Adherens junction;
04540
:Gap junction;
04640
:Hematopoietic cell lineage;
04730
:Long-term depression;
04810
:Regulation of actin cytoskeleton;
04910
:Insulin signaling pathway;
04912
:GnRH signaling pathway;
04930
:Type II diabetes mellitus;
05050
:Dentatorubropallidoluysian atrophy (DRPLA);
05120
:Epithelial cell signaling in Helicobacter pylori infection;
05210
:Colorectal cancer;
|
PubMed ID |
2164210;
2687875;
7685162;
9516479;
11325528;
12154198;
12939402;
14702039;
15358134;
15489334;
16541075;
17344846;
17701904;
19369195;
20007378;
20351256;
21575594;
ALL;
|
Related H-InvDB links |
Similarity Search Tool
|
Database links |
RefSeq |
NA
|
Ensembl |
NA
|
Entrez Gene |
Entrez Gene ID:2065;
|
KEGG GENES |
KEGG GENES(2065);
|
GeneCard |
ERBB3;
*GeneCards is provided free to academic non-profit institutions.
|
etc |
Human-Gene diversity Of Life-style related Diseases;
|
Curation status |
Human curated
|
Notes |
NA
|