H-Inv ID |
HIT000424264 |
H-Inv cluster ID |
HIX0215181
|
H-Inv protein ID |
HIP000192534
|
Accession number |
AK291467.1
|
CAGE tag ID |
NA
|
EST ID |
NA
|
Genomic location
|
Chromosome |
2 |
Location |
2p22.1
|
Position |
39477342-
39664419
|
Strand |
-
|
Transcript feature
|
NO;
|
Coding potential
|
Protein coding;
|
Definition |
Mitogen-activated protein kinase kinase kinase kinase 3; EC=2.7.11.1; Germinal center kinase-related protein kinase; GLK; MAPK/ERK kinase kinase kinase 3; MEK kinase kinase 3; MEKKK 3; |
Similarity category
|
Category: Identical to known human protein(Category I).
|
Identical to known human protein (Q8IVH8)
[Identity/coverage = 99.888%/100.0%] to
Homo sapiens (Human). protein.
|
Gene family / group |
NA
|
Gene symbol/name |
HGNC symbol |
MAP4K3
|
HGNC aliases |
NA
|
HGNC name |
mitogen-activated protein kinase kinase kinase kinase 3
|
DDBJ |
NA
|
UniProt |
MAP4K3
|
EC number |
EC 2.7.11.1non-specific serine/threonine protein kinase;
|
KEGG metabolic pathway |
04150
:mTOR signaling pathway;
04210
:Apoptosis;
04310
:Wnt signaling pathway;
04320
:Dorso-ventral axis formation;
04340
:Hedgehog signaling pathway;
04350
:TGF-beta signaling pathway;
04360
:Axon guidance;
04370
:VEGF signaling pathway;
04510
:Focal adhesion;
04520
:Adherens junction;
04530
:Tight junction;
04540
:Gap junction;
04620
:Toll-like receptor signaling pathway;
04630
:Jak-STAT signaling pathway;
04660
:T cell receptor signaling pathway;
04662
:B cell receptor signaling pathway;
04664
:Fc epsilon RI signaling pathway;
04720
:Long-term potentiation;
04730
:Long-term depression;
04810
:Regulation of actin cytoskeleton;
04910
:Insulin signaling pathway;
04912
:GnRH signaling pathway;
04920
:Adipocytokine signaling pathway;
05010
:Alzheimer's disease;
05210
:Colorectal cancer;
|
PubMed ID |
9275185;
15489334;
17344846;
19369195;
ALL;
|
Related H-InvDB links |
Similarity Search Tool
|
Database links |
RefSeq |
NA
|
Ensembl |
NA
|
Entrez Gene |
Entrez Gene ID:8491;
|
KEGG GENES |
KEGG GENES(8491);
|
GeneCard |
MAP4K3;
*GeneCards is provided free to academic non-profit institutions.
|
etc |
Human-Gene diversity Of Life-style related Diseases;
|
Curation status |
Auto-annotated
|
Notes |
NA
|