Integrated Database and Systems Biology Team

Integrated Database and Systems Biology Team develops an integrated database of all human genes and transcripts, H-Invitational Database (H-InvDB), and study biological phenomena such as evolution and gene expression by computational analyses of information about molecular systems. Also, we carry out the Integrated Database Project of Ministry of Economy, Trade, and Industry of Japan (METI) in collaboration with the Japan Biological Informatics Consortium (JBIC), in order to promote the use of databases in the field of life science.

[Research Topics]

  • Development of an integrated database of all human genes and transcripts
  • Development of gene annotation technology
  • Structure and function of human alternative splicings
  • Integrative annotation of human proteome
  • Evolution of human genes by genomic duplication
  • Diversity of human genes and its effects on gene function
  • Evolution of human gene families by comparative genomics
  • Origins and evolution of tissue-specific genes
  • Data-mining methods for identifying disease-related genes
  • Etc.

[Links]


Biocuration 2010 [10.04.01]

Biocuration 2010, the Conference of International Society for Biocuration, will be held on October 11-14, 2010 in Odaiba, Tokyo. For details, please visit the website.


H-InvDB_7.0 major release [10.02.16]

H-invitational Database(H-InvDB) was renewed. (release 7.0)


Renewal of HEAT[10.01.14]

H-InvDB Enrichment Analysis Tool (HEAT) was renewed. We newly included analysis of common sequence motifs in promoter regions based on the JASPAR database in addition to 8 kinds of annotation such as GO and KEGG pathway. Moreover, HEAT became more useful as it accepts more kinds of IDs and the download function was added. Please try the HEAT.


New Address(2009.11.01)

The address is changed as follows on November 1, 2009.
Aomi 2-4-7, Koto-ku, Tokyo 135-0064 Japan


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